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New Drug Might Boost Tolerance to Alcohol and Cure Hangover

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Researchers at the University of California, Los Angeles (UCLA), have tested a new drug on rats regarding the consumption of alcohol, and achieved stunning results: the subjects not only showed strong resistance to the drink and few signs of a hangover in the following hours but, even after repeated use, didn’t develop alcoholism.

The source of this priceless drug is an Asian tree, the Hovenia Dulcis, which was well-known since the 7th century for the rebuilding properties of its fruit after heavy drinking. The researchers took from the tree the Diyydromyricetin (DHM), a flavonoid that acts as a natural antioxidant, and conducted an experiment: first they gave the rats the equivalent of 15 to 20 bottled beers in two hours and observed the consequences (which were the expected in these cases). Then, they proceeded to do the same after giving the rats a shot of DHM. In this case the results, as said before, were amazing.

It took more time for the rats to pass out and they were able to recover the control of their body much faster. In addition, when two days later they were again offered alcohol, they would drink the same and not more, as happened with the rats that were not given the shot of DHM.

The goal of the researchers, who published their study this week in The Journal of Neuroscience, will be to test the new drug on humans.

Source: InventorSpot, Mail Online

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Shen Y, Lindemeyer AK, Gonzalez C, Shao XM, Spigelman I, Olsen RW, & Liang J (2012). Dihydromyricetin as a novel anti-alcohol intoxication medication. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32 (1), 390-401 PMID: 22219299

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